新型血小板聚集抑制剂研究进展

姜攀

中国药学杂志 ›› 2013, Vol. 48 ›› Issue (3) : 230-233.

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中国药学杂志 ›› 2013, Vol. 48 ›› Issue (3) : 230-233. DOI: 10.11669/cpj.2013.03.017
知识介绍

新型血小板聚集抑制剂研究进展

  • 姜攀
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摘要

目的 血小板的激活和聚集在心血管疾病形成过程中起到核心作用,大量临床试验表明口服抗血小板药物,在有效性、患者耐受性及药物不良反应方面都存在一定不足,作用将以上诸方面内容及国内外对于新型血小板聚集抑制剂的研究进展做一综述。方法 参阅相关文献,对血小板聚集抑制剂的作用机制及临床试验研究现状和临床应用价值进行归纳和综述。结果与结论 一些新型血小板聚集抑制剂已经批准上市,另一些药物也已进入Ⅲ期临床试验。新型血小板聚集抑制剂有许多潜在优势,有利于急性冠脉综合征的防治。

关键词

血小板聚集抑制剂:急性冠状动脉综合征 / 二磷酸腺苷P2Y12受体拮抗剂 / 经皮冠状动脉介入治疗 / 血栓素A2受体拮抗剂 / 凝血酶受体拮抗剂 / 磷酸二酯酶抑制剂 / DZ-697b

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姜攀. 新型血小板聚集抑制剂研究进展[J]. 中国药学杂志, 2013, 48(3): 230-233 https://doi.org/10.11669/cpj.2013.03.017
中图分类号: R973.2   

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